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Buy DIPHENIDINE Online, Diphenidine is a diarylethylamine related to methoxphenidine. It is named for its two phenyl and piperidine groups. Diphenidine ‘s crystalline structure is very similar to MK-801 (Dizocilpine) and shares many of the same effects. These two compounds are homeomorphs. Diphenidine is synthesized in a reaction analogous to the synthesis of PCP. The (R)-enantiomer of diphenidine has a remarkable high affinity as a NMDA receptor channel blocker. Diphenidine acts as an NMDA receptor antagonist. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. NMDA receptor antagonists close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually the famous “hole”. Although vendors of diphenidine have stated the compound acts as a dopamine-reuptake inhibitor and a serotonin reuptake inhibitor with u-opioid affinity and typical dissociative effects, to date diphenidine has not been screened for affinity at the dopamine transporter.

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Buy DIPHENIDINE Online

Buy DIPHENIDINE Online, Diphenidine is a diarylethylamine related to methoxphenidine. It is named for its two phenyl and piperidine groups. Diphenidine ‘s crystalline structure is very similar to MK-801 (Dizocilpine) and shares many of the same effects. These two compounds are homeomorphs. Diphenidine is synthesized in a reaction analogous to the synthesis of PCP. The (R)-enantiomer of diphenidine has a remarkable high affinity as a NMDA receptor channel blocker.

Buy DIPHENIDINE Online, Diphenidine with an IUPAC or systematic name of (1-(1,2-diphenylethyl)piperidine) is a chemical compound that is similar in action to a NMDA receptor channel blocker. The molecular formula for Diphenidine is C19H23N with an average mass of 265.392609 Da and a monoisotopic mass of 265.183044 Da.

Buy DIPHENIDINE Online, Chemical and physical properties of Diphenidine include a heavy atom count of 23, topological polar surface area of 23.5, covalently bonded unit count of 1, feature 3D acceptor count of 1, 3D donor count of 1, feature cation count of 1, feature 3D ring count of 3, and effective rotor count of 4.2.

Buy DIPHENIDINE Online, Diphenidine is a homeomorph of the NMDA receptor channel blocker, MK 801, that has been identified as a designer drug.1 The (S)- and (R)- enantiomers of diphenidine have been reported to inhibit MK 801 binding to NMDA receptors in rat brain membranes with Ki values of 0.13 and 5.25 µM, respectively.1 It has been studied as a neuroprotective agent for the treatment of brain injury following hypoxia.2 This product is intended for forensic and research applications.

Buy DIPHENIDINE Online, First synthesised in 1924, Diphenidine is a dissociative anaesthetic comparable to NMDA antagonists such as 4-MeO-PCP and Ketamine. It makes an ideal substitute for comparable research purposes into the effects of those substances upon the associated receptors. Reports state that it has produced unusual somatic sensory phenomena and anterograde amnesia (forgetting events following application).

Buy DIPHENIDINE Online, Diphenidine acts as an NMDA receptor antagonist. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. NMDA receptor antagonists close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually the famous “hole”. Although vendors of diphenidine have stated the compound acts as a dopamine-reuptake inhibitor and a serotonin reuptake inhibitor with u-opioid affinity and typical dissociative effects, to date diphenidine has not been screened for affinity at the dopamine transporter.

Buy DIPHENIDINE Online, If this is indeed the case, however, it provides an explanation for its euphoric and often stimulating effects. Diphenidine and related diarylethylamines have been studied in vitro as treatments for neurotoxic injury. Diphenidine may be a stronger NMDA receptor antagonist for neurogenis and neurological repair than other more common NMDA receptor antagonistic dissociatives such as ketamine, dextromethorphan, PCP analogs, Iboga and methoxetamine.

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