BUY 5F-AB-PINACA ONLINE

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BUY 5F-AB-PINACA ONLINE, is an indazole-based synthetic cannabinoid that is derived from a series of compounds originally developed by Pfizer in 2009 as an analgesic medication, and has been sold online as a designer drug. 5F-AB-PINACA has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.48 nM and 2.6 nM respectively.[3] Its metabolism has been described in literature. Mouse AtT-20 neuroblastoma cells stably transfected with human CB1 or human CB2 were used for activity evaluation. Prior to the assay, cells were loaded with 90 μL/well of the dye solution without removal of the L-15, giving an initial assay volume of 180 μL/well. Plates were then incubated at 37 °C at ambient CO2 for 45 min. Fluorescence was measured using a FlexStation 3 (Molecular Devices) microplate reader with cells excited at a wavelength of 530 nm and emission measured at 565 nm. Baseline readings were taken every 2 s for at least 2 min, at which time either drug (5F-AB-PINACA) or vehicle was added in a volume of 20 μL. The background fluorescence of cells without dye or dye without cells was negligible. Changes in fluorescence were expressed as a percentage of baseline fluorescence after subtraction of the changes produced by vehicle addition, which was less than 2% for drugs dissolved in assay buffer or DMSO. N-((1S)-1-(Aminocarbonyl)-2-methylpropyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide (5F-AB-PINACA) is an indazole-based synthetic cannabinoid developed by Pfizer in 2009 as an analgesic medication. In January 2015, AB-PINACA became a controlled substance in the USA and 5F-ABPINACA will be prohibited based on the analog law. 5F-AB-PINACA has been sold online as a designer drug.

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BUY 5F-AB-PINACA ONLINE

BUY 5F-AB-PINACA ONLINE, is an indazole-based synthetic cannabinoid that is derived from a series of compounds originally developed by Pfizer in 2009 as an analgesic medication, and has been sold online as a designer drug. 5F-AB-PINACA has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.48 nM and 2.6 nM respectively.[3] Its metabolism has been described in literature.

BUY 5F-AB-PINACA ONLINE,  Mouse AtT-20 neuroblastoma cells stably transfected with human CB1 or human CB2 were used for activity evaluation. Prior to the assay, cells were loaded with 90 μL/well of the dye solution without removal of the L-15, giving an initial assay volume of 180 μL/well. Plates were then incubated at 37 °C at ambient CO2 for 45 min. Fluorescence was measured using a FlexStation 3 (Molecular Devices) microplate reader with cells excited at a wavelength of 530 nm and emission measured at 565 nm.

BUY 5F-AB-PINACA ONLINE, Baseline readings were taken every 2 s for at least 2 min, at which time either drug (5F-AB-PINACA) or vehicle was added in a volume of 20 μL. The background fluorescence of cells without dye or dye without cells was negligible. Changes in fluorescence were expressed as a percentage of baseline fluorescence after subtraction of the changes produced by vehicle addition, which was less than 2% for drugs dissolved in assay buffer or DMSO. N-((1S)-1-(Aminocarbonyl)-2-methylpropyl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide (5F-AB-PINACA) is an indazole-based synthetic cannabinoid developed by Pfizer in 2009 as an analgesic medication. In January 2015, AB-PINACA became a controlled substance in the USA and 5F-ABPINACA will be prohibited based on the analog law. 5F-AB-PINACA has been sold online as a designer drug.

BUY 5F-AB-PINACA ONLINE, also known as 5-Fluoro-AB-PINACA with the IUPAC name of N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide is a white powder. The chemical formula is C18H25FN4O2 with a molecular weight of 349.42 g/mol and a 99% purity with a melting point of 85.3 °C. 5F-AB-PINACA also known as 5-Fluoro-AB-PINACA with the IUPAC name of N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide is a white powder.

BUY 5F-AB-PINACA ONLINE, is an indazole-based synthetic cannabinoid that is derived from a series of compounds originally developed by Pfizer in 2009 as an analgesic medication, and has been sold online as a designer drug. 5F-AB-PINACA has been reported to be a potent agonist of the CB1 receptor and CB2 receptor with EC50 values of 0.48 nM and 2.6 nM respectively.[3] Its metabolism has been described in literature

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